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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa22e5188328ac041b7b0a954b9715b0005291c3b79d91c90124ed9786a81e2c' 
  AND token = 'KIvlJMazhIbyPma8P5A1qw6XGecOAyZV2m1/co9l1BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}