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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3c17c5f477362f70e9c2c23e9d5528823b53d590eb672c5704a007521485a9' 
  AND token = '4imxhXTgeafZASsdwQh8C1pN9FAZkVADby/6iJ2kCeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}