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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1cda457e3d6bfb2a66148cbeb974be2d28f8b767f6a5e332774d5a893e5add' 
  AND token = 'uIPD9BboGOM/v3ziQuWn2fhWBsc8Fh4SX9ugrRvg3vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}