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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9503be4de8ab55620b7ecbfa66302df88d453a9601c933f8e3a9bf4c8d49d48' 
  AND token = 'Yw1G4vLKVrwL1MnNvd+t6IBDWTKc5lBne1JcCqby+bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}