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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd14c890b7f08bc451a0c97d7fbd3250d22e8a07bb0c06de30b584580a52502' 
  AND token = 'wpRRphcKk/x5Ti/6oVsrab8XCo9He0d8h3fYLx9+QoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}