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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c874894d7b21f6b35536a914e4c703bc907cb109782a9a7493268cd3be5ed3c5' 
  AND token = '44lswpi1TjDCwuw34uUs7pPgjL0BcaUMGLC+iuPgEuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}