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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '300543628143244caa570e253e6fa3effa605b3433326992b0449707fd9adf50' 
  AND token = 'f8ffblK+URSeZF3qJopnwbniKQW9f89wClBF9lUH+k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}