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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78be6a49d208594fc427b1a24f3f9a5ffb267b5fb9c770b7575c76810f7aafa' 
  AND token = 'bjQqbH5HO+pGl9oLco0iRDe8xLIEeYXa4oqnLhSirYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}