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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b227f2a02e6e382e6f87e503397957f574227a1d47b463b43c49f0e09dd4eee' 
  AND token = 'HRWQ6n02KWMxce8W8uBPhM2+VzL6gSV+WPP/a0mg77w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}