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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1930e7ae2b11b73a167aa7d63251e2f3ace5f53b9b76e00e1433d782339c4cc' 
  AND token = 'IMCW8hn0P1x5V5qaOPbGry2Oug7HlFUgTOfJxAP3z/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}