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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e2bd071078f8c3e9d831cd73fd0c915d7dadb0cccaec966b33556aae2e8ce7' 
  AND token = 'U7kUO8XEtfMGS2oLjk20cCEdy/6AYhzwSBP000Y03Ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}