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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd679ae3ffb3e61da4582bee59554e7c5d469f9a219b86255895754cc96e2da' 
  AND token = '9YEbpCAl3rSpojqv/TmUfC/+/FaLojL6xNZLKSpuVeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}