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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd53dbdad78f71a2c4a5fa4421efe310e12955c6e0f42be6d6aa7d1088adae89' 
  AND token = 'I1IjGh1/y0zY/U4nMi8+tvq68ujRdVNn7m1x/YWi5Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}