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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5acbef5574f5539292116f4be4324da314d3ee0d5cc77556830c744f276d46' 
  AND token = 'U/tlcBy9P427FJzkXYgUyDRNt1izAcwvCmf2bov66X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}