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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b459bac61222a7daf6c753eb7c3782ce8c7d37f8b852d78e4dacf724c7f6f9' 
  AND token = 'X9F1Degr5aqh6MuwWwtids+ksBCRIou0LkJdcFT96yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}