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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59be4f9423db319e9477fbf957feb3c0b5e23e0f92b6f1025e4206146d3444b5' 
  AND token = 'u+BnwBIxCzPySGg7535NjP9uMRuriy73W3JFQLTHCAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}