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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0518e8799d4b90f4ef4b338048dad81c823ebe366b804040306f9e84d7531250' 
  AND token = '3Db6902kj2wcOHFfgWkZLTwOB1p6PlwwELbjZ6Raji4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}