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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59ecc83dc80e5b8590dbbb102d8c2a67c828fbb7bebe9cda24c805f9e02c166' 
  AND token = 'iCqSUkaoiLVHBCtnFD2SMrJ/HqIGcw4FGNScA/dBo3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}