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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0533bdd568cb0faffd120421c797f21cea62d31360a2115ad40e8016fa3455b7' 
  AND token = 'x2TqYa7CWDxjeXqNIm0wQnnZ91ltN4c8E2WEz3DnjXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}