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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb6da0297b0253b29bb0f2a1cafe1e1d5814571d66948d454e3e0d78f383fc06' 
  AND token = 'c2laDTMsBb1cZBMVNI7N+qoTQpyRLTAZMtx8+mw/yNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}