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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787b2024ef6480abebcc775ce1225d2c0ec42bc0c208de8043b3524eac05478b' 
  AND token = '48qSh+Xf0fwg6fPbcrSMnpRMqP0wf/5/wmyzKzcLK30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}