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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b41546d11448eb790bfcf9f6be2a50b7fbfd0e3deb56d8852e45afe864d225' 
  AND token = 'RZ8Vo6IjxVKO7rScgWbgqBlV/FmZXH060ICxXIS2b5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}