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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12266f6173505cb181ecd1ae54f068323bcc9c66e81027504db6641cbfd48eff' 
  AND token = 'rk99u0eanuBCqcnQ7EPM33tWb735X1IV109CVOReVxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}