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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a473889fbb51e18abe585b450fda4158faa7084a87a366d2d81de56ff2d4ab' 
  AND token = 'L0YifJjklELIk5UXLq3BwSKq2hUre75BzXE8QLlXBuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}