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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543d033740caccb4df22442fc7392882edb0ed9801e8884efeb2c1a0343af01b' 
  AND token = 'Kc22u21I8xZqnZ2mP5MnnMwon9bWL1m3hOqz50Zqeyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}