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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2591b90f89657f3f50d1b9194c41f69e4e00f9d148cb2d82ecf34684f40f3627' 
  AND token = 'ro7vTxVZADHSnyOYu4HZAcNrGU1VAWVKOyh/F++Ufs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}