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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421c519b4fa2f99536dd44a8a09e27ca540dd4724bf54e96996d8f820097aa99' 
  AND token = 'YF5LdR9iLRMr/P6xV2Kl+zRD4uAhfBWl6OE9uePhL/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}