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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81416983fb05a2c0bdaf7a833df3238c148d8c265e3ad1dab45ddfc659447946' 
  AND token = '7u53cvbpWDW8fBxRnz4+IqoOPJPj7ncfxiqoXNjdznk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}