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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d02506445f4b14f6474bfa9d14e1f8fe23ed44f0b259cca76ed73d4d7ee567' 
  AND token = 'O2qniF4Z+X1fVPxh4Myxy9B1o0XnWvDTSXzBN+ApUTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}