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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b48cc415d8c0bda2bfedd282f71840fc0fc93a7b67ba34bf3bedb10cfc68165' 
  AND token = 'PM1GfQ/kk78SaDD2IwoWo2LF0KicdDQoibv5S9+Bv7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}