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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b749340ce58a2706e1ba45680973edc7545c612a0e745471726a7bb02d6dd1' 
  AND token = 'xdbfFu6aHOVWkOWr9YRzwFp6e6sI+PvFjE0YN3fvRyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}