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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1359405b3bd43697ad159115de784a9f6c87d9dd0d96af4ad41318629b18d1' 
  AND token = '3+Hu2dCqwotcfHCul7T9XR9FtQN7ot146VS1BOq26wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}