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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b789726e0f80470b94073c0f8486bcb727bc8a61e1656daf2816cdf1f63d93' 
  AND token = 'Ag6pl/7LDvgpf4ReD0MaPHAEIC7RsMDwiTpd75bsWcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}