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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b720fbe6994b6f6b4b56f13e8a460f739870c1b369f8b967f3971f1848af5c34' 
  AND token = '0T6xU7aCzRJ6ZswSRiP1nXfMHBuFM2YZ1VSYtevzxgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}