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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f448fc6f08445c6b7352f467405293d127e0224b8db596ef5f6121b2df6b0449' 
  AND token = 'tOBFPMBh+Bsn8pPhVnTW4RXqpdjeJ/yaHn0jZeA3Rns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}