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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d1f2018edad2c639d4cb414c7a9b5053b7c206755f2d2a0721e400cb6b4d2e' 
  AND token = 'F5R4TrQdQ0krGrWa1lFUsdoVepRzvdjh0XyZ7wN5jpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}