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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53cd4d3fc50c8823fddb13151c53f7ecb3b082004f0872117f8509c5af9b48c8' 
  AND token = '3w11RjzIzlMwrng5PM+KFI5piovvJR+bWknj7Q/lCX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}