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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c11530df85cebf6d3f5241788830b0d8e3ac2312da66f8d6bf8655e11887df0' 
  AND token = '1yb6+H0Eokv8Bjf9aFr4W4AB5FSiLPfqdqEXJr71lGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}