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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd9b25c184ecdf9753cd0e26d84d82ba07e2a1642c024da97e834082c5053d8c' 
  AND token = '2T5udiYgKDY3UtbOB1kiFON7wmgk53ROSGcpzBdb47g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}