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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72547e850d0725ce1c5897d233a351942668ab76fff158f2b01cd17d1db5d314' 
  AND token = 'kYx8ZXwevF2F7ysr1+vQyZFtyf9hCExz7vtysu2lreQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}