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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afb3d9b5baecf03c4a080fb94bc8d34070b000c8d11c2531f1c4aaa6fad8ef9' 
  AND token = 'JxhO7IRRweJwZ7DCX9IVcDcOz6PmJa45TCWenbZaCEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}