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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4324aeb1a518064b68b7ae45dd7eb3ff71066edcced7240c76a39e1e6637b476' 
  AND token = 'Ckcq12baThSLBYj/NPUzdqQyX0CqNwA/qJ52GhW8IZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}