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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7391c876e2a868877e97fda6627e56725dc8d6420e825be297062a13f80552df' 
  AND token = 'ZUS/uKFM+Caz8bUImA5d/OUUV6/0Shmkqa2y+qWq2I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}