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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d598e44bdc537cf7b0e758a5699d47590f8614ae1dec9f000b4b62c0807a42d' 
  AND token = '7KhmHos7BuQWhS5183ORLQimPldhz0OgdimDcR+Kpfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}