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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '004d4461c9b3cfc6e8c09f8e1926b21aa109681461d4e8873ea61db221dd34d5' 
  AND token = 'VhiMaNN4UonRLCt3agkxylsBjRgOQ+GQgiRqduSI30U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}