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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a240484c749451bfbdb124fc8686185be7328f24bc2b9754b44d244695070cbd' 
  AND token = 's33TTPD0miU9s4byse3ISxqEKB2CV12B/UkWjQZovjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}