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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2c3c14ea0d5f8bbdec2e49a9b0044d0586bb0753154a8f4c2689ac576d1649' 
  AND token = 'TYURbAEhQ/Nv1DgDYXncCMm2o9iPQcxmxMQ1FEhX+mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}