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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf0346ec3a2d1daf84a2e7dccb407ba25870db2af7006383670a9393a440c1ba' 
  AND token = '9I/mO+95JIy4p56FUlP18YqkgBD/6RWnTYVtSPbG/C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}