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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ab4c2968f5f0bf0502ec12766c21f89ec1c4d179045cb495bbc356fa0c37a7' 
  AND token = 'bCN0m/aSM5w2pVQxHpjSLmijgr3M6EqVhOk+/SiSaUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}