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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d80625212f5c60616762e6967d21bc42db2fd12322659446859540f0b1ad78b' 
  AND token = 'ls4Wq7x/jJU4HbM23h32y0UjriSDvW1IXg/HCpGgwHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}